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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Aphclofion: : References:

Virol, G. and M. W. M. K. (2006). Top drug-drug interactions of tadalafil and sildenafil. In:, 1-8.

U. S. Food and Drug Administration (FDA) (2006versible inhibition of phosphodiesterase type 5) and. Washington, DC, USA.

Mayo Clinic (MNC) (2007), “Cialis and nitrates can lower blood pressure, but it is not a controlled substance”. Mayo Clinic Foundation Clinical Research Report, May, 7, page 121.

4. Eli Lilly and Company (2010obtainment of Cialis as a cardiovascular medication) and. Lilly and Company.

5.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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  1. as the cGMP-specific high-molecular-basinginislowheoldease enzyme is induced in response to nitrates and cGMP is induced in response to alpha-blockers. Cialis and nitrates (e.g., nitroglycerin, isosorbide dinitrate) lower blood pressure by approximately 60 and 40 mmHg, respectively. Using cGMP-specific enzyme can increase the likelihood of low blood pressure.

Nitrates (e.g.

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Generic Viagra and Cialis

Compared to brand name Viagra and Cialis, there are quite a few generic options for purchase online in Online Medicals.

Cialis 5 mg (Cialis 5) - Tadalafil (Cialis 5)

Brand Name: Cialis 5 mgis a prescription medicine used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Cialis 5 mg is a type of medicine called a phosphodiesterase type 5 (PDE5) inhibitor, or PDE5 inhibitor. Cialis 5 mg is a type of medicine used to treat ED in men. Cialis 5 mg is a phosphodiesterase type 5 (PDE5) inhibitor. Cialis 5 mg may also be used for purposes not listed in this medication guide.

Cialis 5 mg (Cialis 5) tablets contain the active ingredient tadalafil, which belongs to a class of medicines called phosphodiesterase type 5 (PDE5) inhibitors. Cialis 5 mg is used to treat erectile dysfunction (ED) in men. Cialis 5 mg is also used to treat pulmonary arterial hypertension (PAH), a condition in which the blood vessels in the lungs become narrow.

Cialis 5 mg is also available as a generic medicine known as tadalafil. Generic medicines are usually much cheaper than brand-name medicines. Generic Cialis 5 mg is available in many countries in the world, including the U. S., Europe, Australia and New Zealand.

Cialis 5 mg may also be available as a liquid form in a tablet form. Cialis 5 mg tablets contain the active ingredient tadalafil, which belongs to a class of medicines called PDE5 inhibitors. Cialis 5 mg is also used to treat PAH, a condition in which the blood vessels in the lungs become narrow.

Cialis 5 mg may also be used to treat benign prostatic hyperplasia (BPH), a condition in which the prostate gland enlarges. Cialis 5 mg may also be used to treat high blood pressure (hypertension) in individuals with heart failure. Cialis 5 mg may also be used to treat PAH in individuals with a rare hereditary syndrome called torsades de pointes (torsd’e hyperpotasia).

Cialis 5 mg may also be used to treat pulmonary arterial hypertension (PAH) in individuals with a known or suspected association with tadalafil.